Compartmentalised microfluidic culture systems for in vitro modelling of neurological and neuromuscular microenvironments Maider Badiola, Nanobioengineering group Movement of skeletal-muscle fibres is generated by the locomotion circuit. Failures in any part of the circuit can cause or define the severity of neuromuscular diseases (NMD), such as amyotrophic lateral sclerosis (ALS). Conventional in vitro study models ... Read more
Breaking Paradigms: Delivering insulin orally Ester Caffarel, MIT Biologics have revolutionized disease treatment; however, their rapid degradation and poor absorption in the gastrointestinal (GI) tract generally limit their administration to parenteral routes. Devices for the oral delivery of biologics must aid in both localization and permeation to achieve systemic drug uptake. For this purpose, we ... Read more
Membraneless compartments based on intrinsically disordered proteins: from biology towards new protein materials Paolo Arosio, Institute for Chemical and Bioengineering, ETH Zurich In the last few years, discoveries in biology are revealing that a class of intrinsically disordered protein sequences plays an important role in the formation of cellular membraneless compartments by spontaneous liquid-liquid phase ... Read more
Diabetes, where are we? Anna Novials, PI of the group “Pathogenesis and Prevention of Diabetes” at IDIBAPS/Clinic Hospital of Barcelona and member of CIBERDEM network. Diabetes mellitus (DM) is a group of chronic metabolic disorders all characterized by hyperglycemia. It occurs either when the pancreas does not produce enough insulin or when the peripheral tissues ... Read more
Subjective ratings of emotive stimuli predict the impact of the COVID-19 quarantine on affective states Héctor López Carral, SPECS lab, IBEC The COVID-19 crisis resulted in a large proportion of the world’s population having to employ social distancing measures and self-quarantine. Given that limiting social interaction impacts mental health, we assessed the effects of quarantine on emotive perception ... Read more
Developing new strategies to understand human kidney development and target human disease Patricia Prado Peralta, Pluripotency for organ regeneration group The defence will take place online using the BBCollab platform
Study on the of the interplay between glucose metabolism and SARS-CoV-2 infection exploiting human kidney organoids Núria Montserrat, group leader "Pluripotency for organ regeneration" at IBEC Severe acute respiratory syndrome 2 (SARS-CoV-2) infection leads to a high risk of hospitalization and mortality in diabetic patients. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptor, which is ... Read more
Noves metodologies per al tractament de bacteris creixent en forma de biofilm Núria Blanco-Cabra, Bacterial infections and antimicrobial therapies group at IBEC The defence will take place online, if you wish to attend to this defence, write an email to doctoratmedicina@ub.edu at least 48 hours before the defence.
Deciphering the utility of Galleria mellonella as an infection and toxicity in vivo model Laura Moya, Bacterial infections: Antimicrobial therapies The defence will take place online, if you wish to attend to this defence, you will find the link to access and all the information here
Correlating super-resolution microscopy and transmission electron microscopy for nanoparticle characterisation Teodora Andrian, Nanoscopy for nanomedicine group The functionalization of nanoparticles with surface functional moieties is a key strategy to achieve bioactivity and cell targeting in nanomedicine. The interplay between size and ligand number and distribution is crucial for the formulation performance and needs to be ... Read more