Mechanosensing: harnessing nuclear mechanics to understand health and disease

A study led by IBEC researchers, and published in Nature Cell Biology, shows that applying mechanical force to the cell nucleus affects the transport of proteins across the nuclear membrane. In doing so, this controls cellular processes and could play a key role in various diseases, such as cancer. This entails a novel approach to understanding aspects of cancer invasion and metastasis, opening the door to potential new techniques for diagnosis and therapy.