How does ageing-related stiffening of brain tissue microenvironments affect the regenerative capacity of cns progenitor cells Professor of biology and bioengineering, the Hebrew University of Jerusalem, Israel. Ageing-related stiffening of neuronal microenvironments in the brain generates potent signals that attenuate the regenerative capacity of oligodendrocyte progenitor cells (OPCs) to proliferate and differentiate. We find that ... Read more

Mechanical impact of cell delamination on tissue dynamics, in developmental and tumoral contexts Centre de Biologie Intégrative, CNRS/UMR 5088, Université Toulouse III, Toulouse, France How mechanical forces drive morphogenesis is a fundamental question in the field of biomechanics. Combining imaging, genetics, biophysical and modeling approaches, we found that apoptotic cells, far from being eliminated passively, ... Read more

Development of chemical and synthetic biology tools to generate biotherapeutics and to tackle brain diseases Dr. Benjami Oller-Salvia, IQS In our group we develop chemical and synthetic biology tools to generate biotherapeutics and to tackle brain diseases. In the first part of the talk, I will report our efforts toward developing strategies to construct conditionally-active ... Read more

Spatial single-cell metabolomics reveals metabolic cell states EMBL Recent discoveries put metabolism into the spotlight. Metabolism not only fuels cells but also plays key roles in health and disease. In parallel, emerging single-cell technologies opened a new world of cell types and states previously hidden beneath population averages. Yet, methods for discovering links between metabolism, ... Read more

Towards an evolutionary-driven universal therapy against (intracellular) pathogens Università degli Studi di Milano We are living a time where we believe antibiotics are the cornerstone of any infectious disease-based therapy. It is definitely out of question that antibiotics saved millions of people worldwide in the last century, and that they are still doing it very ... Read more