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IBEC Seminar: Cristina Mayor-Ruiz

IBEC, floor 11, Tower I Baldiri Reixac 4-8, 08028 Barcelona, Spain

Targeted protein degradation: genetic determinants and drug discovery opportunities Cristina Mayor-Ruiz, IRBarcelona Targeted protein degradation is a new therapeutic modality based on drugs that destabilize proteins by inducing their proximity to E3 ubiquitin ligases. Of particular interest are "molecular glue degraders": compounds that can degrade otherwise unligandable proteins by orchestrating direct interactions between target and E3. However, ... Read more

PhD Discussions: Yolanda Castillo and Marc Molina

Assessment of trunk function in patients with spinal cord injury using electromyography and smartphone accelerometry Yolanda Castillo, Biomedical Signal Processing and Interpretation Spinal cord injury (SCI) causes motor and sensory impairment below the level of the injury, but also many other health problems. A common consequence of SCI is the lack of control over trunk ... Read more

IBEC Seminar: Rob Jelier

IBEC, floor 11, Tower I Baldiri Reixac 4-8, 08028 Barcelona, Spain

The effect of gene loss on adaptation | 3D cell shape analysis in embryos Rob Jelier, CMPG - Predictive Genetics and Multicellular Systems University of Leuven In this talk I will summarize two research projects. First, I will report on a large-scale experimental evolution study into the effect of gene deletion on adaptation. We found ... Read more

Online IBEC Seminar: Arnau Hervera

Therapeutic effects of HDAC3 inhibition on spinal injuries and autoimmune demyelinating diseases Arnau Hervera, Molecular and Cellular Neurobiotechnology The molecular mechanisms discriminating between regenerative failure and success remain elusive. While a regeneration-competent peripheral nerve injury mounts a regenerative gene expression response in bipolar dorsal root ganglia (DRG) sensory neurons, a regeneration-incompetent central spinal cord injury ... Read more

Online IBEC Seminar: Irene Marco

Updates on a new lab at IBEC: hyperpolarised magnetic resonance for real-time, in situ monitoring of cell metabolism Irene Marco, Molecular Imaging for Precision Medicine group at IBEC There is a clinical need for non-invasive and reliable markers to diagnose, stage and evaluate treatment response in many diseases such as cancer or non-alcoholic fatty liver ... Read more

PhD Discussions: Enrico Almici and Albert Manzano

Investigating Pathological Extracellular Matrix Architecture The composition and architecture of the extracellular matrix (ECM), and their dynamic alterations, play an important regulatory role on numerous cellular processes. Furthermore, structural and biochemical properties of the ECM are central in regulating cell behavior via mechanical, chemical and topological cues detected by receptors in the cell membrane which ... Read more

PhD Thesis Defence: Ana López Mengual

Sala Graus, Faculty of Biology Barcelona

Factores físicos y moleculares implicados en la migración celular y en el desarrollo de la corteza cerebral. Ana López Mengual, Molecular and cellular neurobiotechnology group Abstract Cell migration acquires special relevance during embryonic development and tissue regeneration. During the development of the adult individual, cells multiply, differentiate and mature, having to move to their destination ... Read more

Online IBEC Seminar: Carlos Aleman

Smart and multifunctional artificial materials for bioengineering Carlos Aleman, Universitat Politècnica de Catalunta (UPC) The research of the " Innovation, Modeling & Engineering in Materials" group in the field of multifunctional materials. Three, different examples of multifunctional systems will be presented: 1) Magnetic electroconductive and self-healing PEDOT:alginate hydrogels for sensing, drug-delivery and energy storage; 2) ... Read more

Núria Montserrat at “TEDxBarcelona – 8+3 charlas para vivir una vida saludable”

Evento anual TEDxBarcelona 2022, una jornada única donde personas extraordinarias presentarán sus ideas para vivir una vida en salud. El evento anual consta de diferentes conferencias divididas en dos sesiones durante toda la jornada, entre ellas, los asistentes podrán disfrutar de una feria donde algunas empresas de Barcelona presentarán sus productos innovadores.1ª Ponencia: 16:00h – 17:30h José Cruset (Director ... Read more

PhD Thesis Defence: Ariadna Marín Llauradó

Auditori Antoni Caparrós, PCB Tower D, c/Baldiri Reixac 4-8, Barcelona, Spain

Mechanical stress in curved epithelia of designed size and shape Ariadna Marín Llauradó, Integrative cell and tissue dynamics group The function of organs such as lungs, kidneys and mammary glands relies on the three-dimensional geometry of their epithelium. How epithelial geometry emerges from mechanical stresses remains poorly understood. To address this question systematically, here we ... Read more