Mechanical signals in the development of the cerebral cortex

The study, published by the journal Frontiers in Cell and Developmental Biology, looks at the mechanical signals and traction forces involved in the migration of Cajal-Retzius cells, a group of neurons with an important role in the development of the cerebral cortex.

A poor function or migration of Cajal-Retzius cells can lead to lissencephaly, a disease manifested by the absence of folds in the cerebral cortex, with a life expectancy of only a few years.

José Antonio del Río, principal investigator at IBEC

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