Mechanical signals in the development of the cerebral cortex

Researchers at the Institute for Bioengineering of Catalonia (IBEC), coordinated by principal investigator José Antonio del Río, are in the media for a study in collaboration with the University of Barcelona (UB) that describes the role of mechanical signals in the formation of the cerebral cortex.

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The study, published by the journal Frontiers in Cell and Developmental Biology, looks at the mechanical signals and traction forces involved in the migration of Cajal-Retzius cells, a group of neurons with an important role in the development of the cerebral cortex.

A poor function or migration of Cajal-Retzius cells can lead to lissencephaly, a disease manifested by the absence of folds in the cerebral cortex, with a life expectancy of only a few years.

José Antonio del Río, principal investigator at IBEC

You can read all the impacts in the media here: