New avenues for identifying and evaluating treatments for CDKL5 deficiency disorder

Researchers from the Institute for Bioengineering of Catalonia (IBEC) have participated in a study led by Imperial College London in which the role of cyclin-dependent protein kinase 5 (CDKL5) in pain perception has been uncovered.

The defective version of the gene that produces this protein is behind CDKL5 deficiency disorder, a rare disease with no cure for which effective treatments will now be testable in mouse model, thanks to the results of this work.