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Fibrosens Project receives funds from AFM-Telethon to develop sensor devices for muscular dystrophy

IBEC researchers Chiara Ninfali (left) and Juanma Fernández (right).

IBEC researcher Juanma Fernández recently has received funding from the French AFM-Telethon to carry out the project “Monitoring of fibrotic processes in 3D skeletal muscle co-cultures for Muscular Dystrophies using plasmonic biosensors”. The objective is to develop multiplexing sensor devices to achieve online, real-time sensing capability to monitor fibrosis markers and evaluate drug response in muscular dystrophy in vitro models.

An artificial muscle to study Duchenne muscular dystrophy

Developed by the IBEC, this system is created using patient cells and represents the first 3D muscle model capable of replicating the damage caused by Duchenne muscular dystrophy. The next phase of this project involves the development of an organ-on-a-chip platform, enabling more efficient preclinical studies of potential drugs and enhanced monitoring of muscle damage. Funding for this research has been provided by Duchenne Parent Project Spain, a non-profit association led by families with children affected by this form of dystrophy.