This is a molecule that is directly linked to the expression of the cellular prion protein found on the surface of nerve cells. The study, led by the IBEC, opens the door to the early detection of Alzheimer’s disease in asymptomatic stages in blood samples, favouring its diagnosis and treatment.
The researcher at the Institute for Bioengineering of Catalonia has been awarded an ERC Consolidator Grant. This prestigious European funding supports excellent scientists and scholars who are consolidating their independent research teams to pursue their most promising scientific ideas. The €2 million grant over 5 years will allow Bolognesi and her team to develop a new method for identifying mutations that lead to the formation of amyloids—aggregates of proteins that contribute to a variety of diseases, including Alzheimer’s and Parkinson’s.
A study led by the Institute of Bioengineering of Catalonia (IBEC) describes the development of an organ-on-a-chip that mimics the human blood-brain barrier. With this system, researchers can study the barrier permeability to different drugs and screen the most effective ones, avoiding animal tests. The device could also incorporate cells from patients to make a personalized study of the disease.
Researchers from the Institute for Bioengineering of Catalonia (IBEC) have developed the most complete atlas up to date of the genetic mutations that cause the formation of amyloid beta fibril, … Read more
