Cell migration Archives - Institute for Bioengineering of Catalonia

March 24, 2023March 24, 2023

The movement of cancer cells depends on the topography and stiffness of their environment

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A recent IBEC study has described how cells contact guidance is not only topography-dependent but also affected by the stiffness of the environment. The work highlights the importance of considering … Read more

May 28, 2020January 23, 2019

Large-scale curvature sensing by directional actin flow drives cellular migration mode switching

Cell migration is an essential biological process that drives tissue and organ formation during embryo development, and also helps protect the body through immune response and wound healing mechanisms. The shape changes necessary for cell migration depends on dynamic organization and force generation from the cell’s internal actomyosin cytoskeleton, which is made up of structural actin filaments and contractile myosin motor proteins.

Reorganization of these components enables two mechanisms of cell migration.