Xavier Trepat Archives - Institute for Bioengineering of Catalonia

September 14, 2023

Preventing the tissue’s response to stiffness may be key to slowing the progression of breast tumors

A study led by the Institute of Bioengineering of Catalonia demonstrates that laminin, a protein present in breast tissues, prevents the effects of stiffening, protecting cells against tumor growth. While the mechanism has been demonstrated in vitro, persuasive indications suggest its potential applicability in vivo, as observed in patient samples.

June 29, 2023June 29, 2023

The internal clock of our cells is influenced by mechanical forces

A doctor in medical gloves holds an hourglass.

IBEC researchers uncover how mechanical forces disrupt the circadian clock in cells, the mechanism governing daily physiological changes. The finding may help to better understand aging and specific diseases, like … Read more

May 8, 2023

Daniel Navajas: 30 years dedicated to mechanobiology

Last May 5, on the occasion of Professor Daniel Navajas’ retirement, the IBEC held the symposium Before Mechanobiology had a name. The event paid tribute to the IBEC researcher’s exciting … Read more

February 14, 2023February 7, 2023

Cancer cells move to rigid environments like droplets

Researchers from the Institute of Bioengineering of Catalonia (IBEC) and the University of Barcelona (UB) uncovered a similarity between liquid droplets and cell groups, revealing that surface tension helps cells to … Read more

June 13, 2022

Mechanosensing in the media

IBEC researchers led by Pere Roca-Cusachs and Xavier Trepat appears in the media for a study that opens doors for new research into cancer therapies and diagnostics.

June 12, 2022

EMBL-IBEC Conference in the media

The EMBL-IBEC Conference, a three-day conference organized by the Institute for Bioengineering of Catalonia (IBEC) and the European Molecular Biology Laboratory (EMBL), is featured in the journal ARA where international experts discussed how to reproduce human diseases in living systems generated in the laboratory.

December 22, 2021December 16, 2021

Researcher Xavier Trepat wins the “Constantes y Vitales” award for his pioneering contributions to the mechanobiology field

The ICREA Research Professor at the Institute for Bioengineering of Catalonia (IBEC), Xavier Trepat, has been awarded with the “Constantes y Vitales” Award for Talent in Biomedical Research, awarded by the Atresmedia group, for his contributions to the field known as mechanobiology, that studies the effect of physical forces on living systems and their implication in pathologies such as cancer.

July 5, 2021June 22, 2021

The intestinal organoids hit the media

The group led by Xavier Trepat at IBEC, together with Marino Arroyo, associate researcher at IBEC, and other international collaborators have developed intestinal organoids and measured cellular forces in order to decipher how the inner wall of this vital organ folds and moves.

June 21, 2021June 21, 2021

Researchers discover how the intestinal epithelium folds and moves by measuring its forces

An international team led by Xavier Trepat at IBEC, with support from “La Caixa Foundation, measures the cellular forces in mini-intestines grown in the laboratory, deciphering how the inner wall of this vital organ folds and moves.

January 21, 2021

Mechanical forces, half of the alphabet to understand life

Xavier Trepat and international experts remind us in a piece published in the Journal Nature by science writer Amber Dance, the crucial role of physics in order to understand biological entities such cells and organs, both in health and disease. In words of Trepat: “Understanding a cell without physics is like trying to write a book with only half the letters of the alphabet”.