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Physical forces regulate cell division

Researchers at IBEC have discovered that cell division in epithelial tissues is regulated by mechanical forces.

This revelation could potentially open avenues to a greater understanding of the uncontrolled proliferation of cancer cells in tumors, and their possible regulation by means of physical forces.

Publishing in the June edition of Nature Cell Biology, the research group of ICREA professor Xavier Trepat, group leader at IBEC and associate professor at the University of Barcelona (UB), describe how the mechanical state of epithelial tissues – the continuous sheets of cells that cover all the exposed surfaces of the body – is related to the cell cycle and cell division.

A full house for nanotoxicity day

Yesterday Nanomed Spain-organised ‘Jornada sobre Nanotoxicidad’ (Workshop on Nanotoxicity) welcomed almost 100 attendees from all over Spain.

The day focused on a new discipline, the study of toxicity produced by the effect of nanoparticles and nanomaterials. Nanotoxicity has emerged as manufactured nanoparticles can have properties and effects that are very different from those of the same materials in conventional sizes, or can have the same dimensions as certain biological molecules and interact with them, posing new risks to health.

Super-resolution imaging guides the design of biocompatible microswimmers

Two IBEC groups have clubbed together to combine their expertise and reveal new knowledge that could advance the design of micro- and nanomotors for applications in health.

By harnessing the unprecedented resolution of Lorenzo Albertazzi’s group’s STORM microscope, Samuel Sánchez’s group – in collaboration with Erik Schäffer’s group at the University of Tübingen – have been able to reveal new information about how their enzyme-powered nanomotors achieve motion.