Artificial smell to control food quality
Research news
RAS gene and tissue physics act in tandem to drive cancer processes
Researchers from IBEC, the UCL (UK), UPC (Spain) and the TU/e (Netherlands) show that activation of the RAS oncogene (a mutation occurring in approximately 30% of human cancers), induces tumour features in an epithelium via coordinated physical changes of all cells forming the affected tissue. Published in the scientific journal Science Advances, the new work suggests that future cancer treatments should target both the biological processes underlying the disease and the evolving mechanical structure of the affected tissue.
New biosensor detects inflammatory marker in muscle with high sensitivity
In a recent publication in the journal Nanophotonics, IBEC researchers present a new biosensor for the direct and sensitive detection of the protein interleukin-6 in muscle, an indicator of inflammation and potential disease, proving the high performance of the device on bioengineered 3D skeletal muscles. This new approach may result in a promising tool for measuring the efficacy of drug candidates for diseases where inflammation is present such as muscular dystrophy.
Personalised medicine to beat pediatric leukemia
IBEC researchers have used a state-of-the-art analysis technique to evaluate new drug combinations to successfully treat acute lymphoblastic leukemia. This study brings personalised medicine closer to the clinic for this cancer type.
A chip against chronic bacterial infections
IBEC researchers develop a device that allows to grow biofilms and analyze their susceptibility to different antibiotics in a simple way and using patient samples. BiofilmChip, a low-cost, easy-to-use diagnostic device, opens the way to finding effective and custom treatments against chronic infections produced by biofilms.
A new 3D muscle model will allow the study of aging and the evaluation of drugs and cosmetics
IBEC researchers develop a three-dimensional model of muscle tissue using bioprinting and tissue bioengineering techniques that allow reproducing their strength, contraction and aging profiles. The new model will have potential applications in fields such as biomedicine, cosmetics and robotics. In addition, it will open the doors to the study of morphological and functional alterations caused by muscle aging.
High-intensity rehabilitation boosts recovery after a stroke
A retrospective analysis performed by researchers from the Institute for Bioengineering of Catalonia (IBEC) and University College London (UCL) has found that high-intensity therapy beginning within 6 months post-stroke offers the best rehabilitation outcomes, suggesting that standards of care offered by many healthcare systems should be re-analysed.
Researchers uncover the reason for “Living wires” extraordinary electrical properties
An international study co-authored by IBEC’s researchers has identified nickel as a key conductive component in the wires found in cable bacteria. This ground-breaking finding, obtained by combining high-resolution microscopy, spectroscopy and chemical imaging, has been published in the prestigious journal Nature Communications.
Cellular push and pull, a key to the body’s response to processes such as cancer
Researchers, led by Pere Roca-Cusachs at the Institute for Bioengineering of Catalonia (IBEC) discover how force dynamics affect cells, and living tissues. The results give an insight into the critical mechanical processes that occur in different diseases such as cancer.
Researchers discover how the intestinal epithelium folds and moves by measuring its forces
