An IBEC-led study has demonstrated the ability of colorectal cancer stem cells to change their mechanical properties, facilitating the successful metastatic process. They did this using tumour organoids derived from patient cells. These findings could contribute to the development of new strategies to treat and prevent metastasis in colorectal cancer.
Last Friday IBEC hosted an exclusive talk with distinguished bestselling author Siddhartha Mukherjee. At the event, which was attended by more than 120 people, Mukherjee presented his latest book “The Harmony of Cells” and shared an interesting talk about the latest advances in advanced therapies with IBEC researchers.
Two studies led by IBEC have successfully mimicked the transdifferentiation process of the neuroblastoma vasculature in in vitro models. These models, one in 2D and the other on a microfluidic chip, provide platforms for identifying new biomarkers and designing effective therapies against this type of cancer.
The project focuses on developing a chip that will serve as a model for testing new drugs to treat neuroblastoma, a childhood brain cancer. The research has received €200,000 in funding and is led by Aránzazu Villasante, Senior Researcher at IBEC.
Once again, experts in nanomedicine from various fields gathered in Barcelona on the occasion of World Cancer Day. The meeting provided an opportunity to showcase the latest innovations in nanomedicine for combating cancer, covering topics such as early diagnosis, controlled drug release, and radiotherapy employing nanoparticles.
The research, which was conducted on mice, demonstrates how these tiny nanomachines are propelled by urea present in urine and precisely target the tumour, attacking it with a radioisotope carried on their surface. Led by the IBEC and CIC biomaGUNE, the study opens the door to new, more efficient treatments for bladder cancer.
The start-up specializes in the development of biocompatible nanorobots capable of delivering drugs to difficult-to-treat tumors more efficiently and safely than current therapies. Nanobots Therapeutics is the third investment in … Read more
A study led by the Institute of Bioengineering of Catalonia demonstrates that laminin, a protein present in breast tissues, prevents the effects of stiffening, protecting cells against tumor growth. While the mechanism has been demonstrated in vitro, persuasive indications suggest its potential applicability in vivo, as observed in patient samples.
Samuel Sánchez has successfully secured an “ERC Proof of Concept” grant, provided by the European Research Council (ERC), to explore the application of his nanorobots in the treatment of mucus-secreting tumors. This prestigious grant enables researchers to assess the feasibility and potential for knowledge transfer of their research projects.
IBEC researchers uncover how mechanical forces disrupt the circadian clock in cells, the mechanism governing daily physiological changes. The finding may help to better understand aging and specific diseases, like … Read more