A low-cost ventilator for areas with limited means

A project led by the University of Barcelona to which IBEC Group Leader Daniel Navajas has contributed has created a non-invasive low-cost ventilator to support patients with respiratory diseases in areas with limited means.

Non-invasive ventilators are usually used to treat patients with respiratory failure: for example, those with severe complications due to COVID-19.

PeriCord, a bioimplant for infarcted hearts

The journal “EBioMedicine” of “The Lancet” has just published the procedure that allowed the creation, last year, of the “PeriCord”, the first human cardiac bioimplant, in which development the Institute for Bioengineering of Catalonia (IBEC) played a key role.

In May 2019, a collaboration between the ‘Germans Trias i Pujol’ Hospital, the Blood and Tissue Bank (BST) and IBEC took a step forward for heart patients combining medicine, science and engineering.

First bioimplant with stem cells to regenerate the heart

The team led by Daniel Navajas, principal investigator at IBEC, together with the Blood and Tissue Bank have developed a bioimplant of stem cells of about 16 cm² that is applied directly to the heart. The bioimplant is composed of decellularised human pericardium and enriched with stem cells from umbilical cord, of great plasticity and, therefore, capable of regenerating tissues.

IBEC bioengineers contribute to a heart implant

A group from the Institute for Bioengineering of Catalonia (IBEC) led by Daniel Navajas contributes to an operation designed to repair the heart tissue of a 70-year-old patient who had suffered a heart attack. This was made possible by the creation of a bioimplant enriched with stem cells. The operation is the result of the joint work of scientists, doctors and engineers over more than ten years.

Sleep apnea could promote tumor growth in the young

A study published in the American Journal of Respiratory and Critical Care Medicine has revealed that sleep apnea could promote the growth of lung cancer in younger individuals.

Researchers from IBEC, the University of Barcelona and Hospital Clinic show that, contrary to expectation, age could be a protective factor against the rapid tumor development induced by this respiratory disturbance of sleep and its immediate consequence, intermittent hypoxia.

Young at heart: novel temporal window of cardiac regeneration

A study carried out at CMR[B] in collaboration with IBEC and the UB has established that the ability of the heart to regenerate after a wound is related to the stiffness of its cellular environment and not only to the proliferative capacity of the cardiac cells, narrowing the window of regeneration to 48 hours after birth.

The research, published in Science Advances, paves the way for the development of therapies based on the pharmacological modification of the extracellular matrix to promote tissue regeneration after a heart attack or stroke.