Non-invasive analysis technique contributes to a better understanding of COPD

Some research published in PLOS ONE represents a new step towards translating IBEC’s basic research – specifically the novel signal processing and interpretation algorithms developed by Raimon Jané’s group – to clinical applications in hospitals.

The group collaborated with the Hospital del Mar-IMIM in Barcelona to tackle the current lack of instruments for assessing respiratory muscle activation during the breathing cycle in clinical conditions.

Read more…

A cellular model to help study the relationship between neurodegenerative diseases

From the cells of a patient with a rare neurodegenerative disease, Gerstmann-Sträussler-Scheinker syndrome (GSS), researchers at IBEC have managed to generate neurons that also present parallel neurodegenerative processes unrelated to the syndrome.

The striking image on the left shows a mass of neurons derived from GSS-affected pluripotent stem cells (iPS), developed in José Antonio Del Río’s lab.

Read more…

The most efficient single-molecule diode ever made

Researchers have created the most efficient single-molecule diode ever.

Diodes are common in everyday electronic devices, in which they control the current by allowing it to flow in one direction while blocking it in the opposite direction. The researchers, working at the University of Barcelona (UB) and IBEC, have created one of just 1 nanometer in size with a rectification ratio – the ratio of the current that flows in one direction compared to the other – several orders of magnitude higher than previously.

Read more…

Screening improvements for asthma and obstructive pulmonary disease patients

Some IBEC research published in PlosOne offers a step towards better screening of patients with asthma and other sufferers of obstructive pulmonary diseases.

The new integrated approach to continuous adventitious respiratory sound (CAS) analysis, developed by Raimon Jané’s Biomedical Signal Processing and Interpretation group within the framework of IBEC’s Joint Research Unit with the Institut d’Investigació Hospital Germans Trias i Pujol (IGTP), improves assessment in the clinic.

Read more…

3D printing biocompatible hydrogels

IBEC researchers have laid the groundwork for faster advances in 3D bioprinting for regenerative medicine by creating a system of ink and matrices that offers a solid basis for tissue regeneration.

Due to their high water content, hydrogels are highly attractive biomaterials for 3D printing as efficient ‘surrogates’ for the extracellular matrix, onto which cells can be cultured. However, while they are relatively easy to produce using a method called extrusion printing, their stability and structural integrity can weaken when they’re in contact with biological fluids or extracellular matrices.

Read more…

How tumor cells hijack healthy cells to promote metastasis

In a study published today in Nature Cell Biology and supported by Obra Social “la Caixa”, researchers at IBEC have identified an interaction between two proteins that enables cancerous cells to use the physical forces of healthy cells to start tumor metastasis.

Metastasis, responsible for the majority of deaths in patients with cancer, is the process by which cancer cells separate from the original tumor to form new tumors in other organs or tissues of the body.

Read more…

Light-regulated drugs as analgesics

A new study involving scientists from IBEC, IQAC/CSIC and CNRS in France uses light-regulated drugs to alleviate the negative emotions associated with chronic pain.

Chronic pain is pain that lasts more than six months. Its origin can be both physiological and emotional, and it is accompanied by symptoms such as hypersensitivity, anxiety and depressive behavior. It has no cure, treatment is difficult, and current drugs don’t alleviate the symptoms.

Read more…

New DNA-based technique for depositing materials with a resolution of less than 10 nanometers

adnorigamiA study led by CSIC and involving IBEC researchers proposes a new technique using molecules ‘a la carte’ to obtain nanoscale surfaces that will have many useful applications in microelectronics and biomedicine. The work has been published in the journal Advanced Materials.

The new method means that researchers can obtain nanoscale surfaces with many molecules arranged in an ordered way.

Read more…