The study of physical forces in tumor progression
Xavier Trepat
Group leader
Bioengineering against cancer
Xavier Trepat and Pere Roca-Cusachs, group leaders at IBEC, appear on the journal “ABC” explaining their research project that they will carry out thanks to funding from “la Caixa” as part of the «Health Research Call ».
Cell Migration Virtual Seminars: Xavier Trepat
Mechanobiology of epithelial folding and migration in intestinal organoids Xavier Trepat, Integrative cell and tissue dynamics group More information here Registration here
Bioengineering against cancer: IBEC researchers receive funding from La Caixa
IBEC researchers Elena Martínez, Xavier Trepat and Pere Roca-Cusachs aim to understand the processes that promote metastasis in colorectal cancer using innovative bioengineering tools, such as bioprinting and microscopy capable of revealing forces at the cellular level.
The results will be translated into a device that will recreate the tumor environment from cancer cells derived from patients, as well as a new technology that will allow to visualize how physical forces affect the nuclei of metastatic cells.
How can we measure mechanical stress in living tissues?
A team of experts from the Institute for Bioengineering of Catalonia (IBEC) has published a review in the journal Nature Reviews Physics detailing the different techniques used to calculate mechanical stress in tissues, both in cell cultures and in vivo. Determining these mechanisms of mechanical stress is crucial to study processes linked to morphogenesis, homeostasis, and diseases such as cancer.
In order to work properly, living tissues need to continuously move, divide, reshape and perceive their microenvironment. In other words, they need to withstand certain mechanical stress derived from contact.
IBEC researchers explain “Durotaxis”, a cell migration mechanism with a potential role in several diseases
Xavier Trepat, group leader of the “Integrative cell and tissue dynamics” at IBEC together with Raimon Sunyer, Senior researcher in Trepat’s lab, have written a Primer in Current Biology magazine on “Durotaxis”, a cell migration mechanism that might have a role in several disease states that include the stiffening of tissues.
Xavier Trepat, group leader of the “Integrative cell and tissue dynamics” at IBEC together with Raimon Sunyer, Senior researcher in Trepat’s lab, have written a Primer in Current Biology magazine on “Durotaxis”, a cell migration mechanism that might have a role in several disease states that include the stiffening of tissues.Embryo development, tumour progression or the immune response against pathogens requires cell migration.
The European Research Council awards funding to 10 projects in Catalonia
Several media channels have reported this year’s European Research Council grants to various projects being undertaken in Catalonia. Among these projects is that of Xavier Trepat, group leader at IBEC.
Several media channels have reported this year’s European Research Council grants to various projects being undertaken in Catalonia. Among these projects is that of Xavier Trepat, group leader at IBEC.Xavier Trepat receives the ERC Advanced Grant to lay the basis of a new generation of biological robots
The researcher at the Institute for Bioengineering of Catalonia (IBEC), Xavier Trepat, has received the prestigious ERC Advanced Grant awarded by the European Research Council (ERC) worth 2.5 million euros.
Thanks to this grant the expert and his group will be able to study the mechanical properties of the epithelium in 3D and to lay the foundations for a pioneering technology called “Epifluidics”, which will allow the design of biological robots.
The broom challenge
Xavier Trepat reveals to the Ara journal the secret behind the famous boom challenge.
Xavier Trepat reveals to the Ara journal the secret behind the famous boom challenge.“The silent revolution of the mini-organs” Xavier Trepat in the ARA newspaper
