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Reducing animal testing with 3D Bioprinting: European project BRIGHTER brings new light

The European project BRIGHTER, coordinated by IBEC, is developing a new technology to produce functional human tissues as an alternative to animal experimentation in the field of biomedical research. This light-based 3D bioprinting technology fabricates tissues by patterning three-dimensional cell cultures. In the future, it could be even used to produce organs in the laboratory.

Nanomedicine against cancer brings together hundred experts

Nanomed, the Spanish nanomedicine platform coordinated by the Institute for Bioengineering of Catalonia (IBEC), organized with the Germans Trias i Pujol Institute (IGTP), the sixth edition of a conference designed to present the advances against cancer, from early diagnosis and controlled drug release, up to nanoparticle radiation therapy.

Does 3D bioprinting improve cancer survival?

Elena Martínez, group leader at IBEC and professor at the University of Barcelona (UB), is interviewed for the Big Vang section of La Vanguardia expaining her project to develop organs on a chip to improve the survival of patients with colorectal tumor metastases.

Bioengineering against cancer: IBEC researchers receive funding from La Caixa

IBEC researchers Elena Martínez, Xavier Trepat and Pere Roca-Cusachs aim to understand the processes that promote metastasis in colorectal cancer using innovative bioengineering tools, such as bioprinting and microscopy capable of revealing forces at the cellular level.

The results will be translated into a device that will recreate the tumor environment from cancer cells derived from patients, as well as a new technology that will allow to visualize how physical forces affect the nuclei of metastatic cells.

IBEC leads three new European projects

Bioengineering is a core discipline for the medicine of the future, and Europe knows that. Proof of this is that the European Union (EU) has granted during the last months the coordination of three European projects to the Institute for Bioengineering of Catalonia (IBEC) to continue combining medicine, science and technology with the aim of improving people’s health.

The first one is the BRIGHTER project that is led by Professor Elena Martínez, the head of the ‘Biomimetic Systems for Cell Engineering’ group. The EU has contributed to this initiative that will be used by the consortium partners to develop an innovative high resolution 3D bioprinting technology able to fabricate 3D cell culture substrates which could be useful to produce artificial organs in the future.

Elena Martínez from IBEC granted by the European Commission to bring research to the market

Elena Martínez, Group Leader at IBEC and UB Professor, has been awarded the prestigious “Proof of Concept” grant of the European Research Council (ERC). With her “GUT3D-PLATE” project, Martínez and her team at the “Biomimetic systems for cell engineering” group will further develop technology to fabricate ready-to-commercialize 3D cell culture substrates mimicking the intestinal physiology.

A research team develops a Mini-Factory of Human Cardiac Tissue

A system developed by researchers from the Institute for Bioengineering of Catalonia (IBEC) and the Centre of Regenerative Medicine in Barcelona (CMR[B]) is capable of producing tissues in a laboratory that simulate the behaviour of the human heart. The tissues produced by this bioengineering system could be used to pre-evaluate the toxicity of drugs in the heart without using animal models.

Cardiovascular diseases are currently one of the leading causes of death worldwide. However, the factors that motivate or accentuate such heart diseases sometimes hide behind relatively unknown elements. Among other causes, drugs that are useful for curing or alleviating certain diseases can, at the same time, have side effects on other organs such as the heart, which experts refer to as cardiotoxicity.

New Culture Technology for Functional Intestinal Assays

During the last decade, intestinal organoids have emerged as a crucial tool to study intestinal biology in vitro. However, their sphere-like geometry limits the access to the organoid’s lumen hampering their use in many functional experiments where independent access to the different sides of the epithelium is required.

IBEC researchers lead a European project to develop a high resolution 3D bioprinting technology

A group of experts at Institute for Bioengineering of Catalonia (IBEC) lead the European project BRIGHTER (Bioprinting by light-sheet lithography: engineering complex tissues with high resolution at high speed), an initiative to develop an innovative and high resolution 3D bioprinting technology able to produce functional tissues.

ERC President visits IBEC

The President of the European Research Council, Jean-Pierre Bourguignon, visited last May 15th the Institute for Bioengineering of Catalonia (IBEC).

The event was inaugurated by IBEC’s Director, Josep Samitier, who presented an overview on the cutting-edge research carried out at the institute in the fields of bioengineering and nanomedicine.

Afterwards, ERC Grantees working at IBEC had the opportunity to explain the impact of ERC grants on their professional careers and established a dialogue with ERC President on the past, present and future of the European Research Council.