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Xavier Trepat

Group leader

La Vanguardia: Investigadores catalanes recrean de forma fidedigna el ambiente tumoral para atacar el cáncer

Investigadores del IBEC y del Hospital del Mar han desarrollado MIRO, un dispositivo que recrea fielmente el entorno tumoral con células de pacientes. Esta innovadora tecnología permite estudiar la interacción celular y probar tratamientos personalizados, mejorando la eficacia de la inmunoterapia contra el cáncer. Investigadores catalanes recrean de forma fidedigna el ambiente tumoral para atacar … Read more

Researchers develop a device that replicates tumours to study the efficacy of immunotherapy treatments

The Micro Immune Response On chip (MIRO) allows tumours and their environment to be replicated in order to understand their response to treatment. The device, which has already been successfully tested on breast cancer samples, could be key to developing new treatments and determining the most appropriate therapy for each patient in a personalized way. The work, published in Nature Communications, is the result of a collaboration between the Institute for Bioengineering of Catalonia and the Research Institute of the Hospital del Mar.

Regió 7: Científica solsonina formada a Harvard: “A internet hi confirmes qualsevol mentida”

En una entrevista amb Regió7, la científica solsonina Janet van der Graaf reflexiona sobre la facilitat de trobar informació a internet que confirmi qualsevol afirmació, independentment de la seva veracitat. Aquesta situació planteja reptes per a la comunitat científica i per a la societat en general, ja que la sobreabundància d’informació pot dificultar la distinció … Read more

ABC: Espaldarazo a la investigación biomédica premium

Xavier Trepat, investigador del Instituto de Bioingeniería de Cataluña (IBEC), lidera un proyecto innovador financiado por la convocatoria CaixaResearch 2024. Su equipo ha desarrollado una tecnología que replica el ecosistema de un tumor de colon en un chip. Este avance permitirá estudiar por qué algunas inmunoterapias no funcionan en este tipo de cáncer, analizando cómo … Read more

Three IBEC researchers selected in the CaixaResearch 2024 call to lead health research projects

IBEC researchers Benedetta Bolognesi, Xavier Fernàndez Busquets and Xavier Trepat have been selected in the CaixaResearch 2024 call to lead their own research projects. The grants will provide financial support for the scientists to carry out their research in key areas such as cancer, malaria and amyotrophic lateral sclerosis.

Bioengineering for Emergent and Advanced Therapies at the 17th IBEC Symposium

IBEC’s 17th Annual Symposium focused on ‘Bioengineering for Emergent and Advanced Therapies’, one of IBEC’s key application areas. Around 300 people attended the event, including local and international researchers. It was a multidisciplinary environment in which experts from other centres and the IBEC community itself had the opportunity to present their projects and share knowledge.

Scientists create leader cells with light

A study led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thought, but that all cells participate in the process. These findings are relevant to the design of treatments to stop tumour invasion or accelerate wound healing, physiological processes closely linked to cell migration.

Scientists discover how the physics of colon cancer cells contributes to metastasis

An IBEC-led study has demonstrated the ability of colorectal cancer stem cells to change their mechanical properties, facilitating the successful metastatic process. They did this using tumour organoids derived from patient cells. These findings could contribute to the development of new strategies to treat and prevent metastasis in colorectal cancer.