A new method confirms the impact of COVID-19 confinement measures on mental health and well-being

This technology opens the door to potential applications in fields such as organ transplantation and engineering, drug screening and disease modelling.
The study, published in the journal Virulence, finds that the class II ribonucleotide reductase enzyme (RNR) plays a key role in frequent lung infections, for example, those that occur in patients with cystic fibrosis.
The defective version of the gene that produces this protein is behind CDKL5 deficiency disorder, a rare disease with no cure for which effective treatments will now be testable in mouse model, thanks to the results of this work.
The research was led by Jan van Hest and Laoi Abdelmohsen from the Institute of Complex Molecular Systems at TU/e in collaboration with Samuel Sánchez from the Institute for Bioengineering of Catalonia (IBEC) in Barcelona, as well as researchers based in China and the UK.
Nature Reviews Materials journal has published an article signed by scientists from the Barcelona Supercomputing Center (BSC), the Universitat Politècnica de Catalunya (UPC) and the Institute for Bioengineering of Catalonia (IBEC) outlining the great possibilities that artificial intelligence offers towards the progress in the design and development of biomaterials.
This therapy, based on synthetic vesicles, could considerably reduce the dose and duration of antimicrobial treatments, thus reducing the danger of generating resistance to antibiotics of pathogens such as those leading to tuberculosis.
Samuel Sánchez, Group Leader at the Institute for Bioengineering of Catalonia (IBEC) co-authored this piece, alongside world-renowned experts in bioengineering and cell synthesis.
To carry out the investigation, they will be allowed to use the supercomputer installed in France.
In order to work properly, living tissues need to continuously move, divide, reshape and perceive their microenvironment. In other words, they need to withstand certain mechanical stress derived from contact.